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KMID : 0931320090090010047
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대한상부위장관.헬리코박터학회지
2009 Volume.9 No. 1 p.47 ~ p.51
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Diagnostic Yield of Gastroscopic Biopsy in Advanced Gastric Cancer
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Ahn Jae-Hong
Chun Hoon-Jai
Koo Ja-Seol
Lee Hong-Sik
Lee Sang-Woo
Choi Jai-Hyun
Park Jong-Jae
Kim Seung-Young
Kim Jin-Nam
Jung Sung-Woo
Kim Dong-Il
Park Sun-Min
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Abstract
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Background/Aim : To evaluate diagnostic yield of gastroscopic biopsy of advanced gastric cancer (AGC) according to tumor location, biopsy site, endoscope and endoscopist.
Methods: A prospective study was carried out in 103 AGC patients. We obtained gastroscopic biopsies at the inner, top, outer margin, base and tumor island in ulcerative type cancers and random biopsies in the Borrmann type 1 and 4 cancers.
Results: The positive rate of gastroscopic biopsy was good at inner, top margin and base in the antrum and body. At the angle, positive rate of inner margin and base were higher than other sites. According to the experience of endoscopist, positive rate of Borrmann type 3 cancer by experts was 95.9%, compared with 92.6% of non-experts. However, same results were showed in the Borrmann type 1, 2, and 4 cancers between the two groups.
Conclusions: For improving diagnostic yield of gastroscopic biopsy for histologic confirmation of AGC, it should be started at the top margin which is easy to approach. At least, three biopsies at the top, inner margin and base are necessary for the diagnosis of AGC.
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KEYWORD
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Diagnosis, Gastroscopic biopsy, Advanced gastric cancer
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